6.7

Mutations

AP Biology

Mutations

Point mutations: single nucleotide changes

Conservative vs non-conservative missense mutations

Frameshift mutations

Comparing mutation severity

Sickle cell disease: the classic AP Biology mutation case study

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Heterozygous advantage

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Chromosomal mutations

Causes of mutations

Spontaneous mutations

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Induced mutations (mutagens)

DNA repair mechanisms

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Mutations in different cell types

Mutations and evolution

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Biotechnology connections

Vocabulary