Regulation of Gene Expression
Why regulate gene expression?
- •
- •
- •
- •
Levels of gene regulation in eukaryotes
Level 1: Chromatin remodeling (epigenetic regulation)
- •
- •
- •
Level 2: Transcriptional regulation (most important level)
Regulatory DNA sequences
Transcription factors
- •
Prokaryotic gene regulation: operons
What is an operon?
The lac operon (inducible)
- •
- •
The trp operon (repressible)
Level 3: Post-transcriptional regulation
RNA interference (RNAi)
- •
- •
- •
- •
- •
Level 4: Translational regulation
- •
- •
- •