5.6

Chromosomal Inheritance

AP Biology

Chromosomal Inheritance

The chromosome theory of inheritance

Evidence: Thomas Hunt Morgan and fruit flies

Linked genes

Gene linkage

Recombination frequency and genetic mapping

Constructing a genetic map

Sex chromosomes

Human sex determination

X-inactivation (Barr bodies)

Chromosomal abnormalities

Nondisjunction

Human aneuploidies

Chromosomal structural abnormalities

Translocation and cancer

Genomic imprinting

Vocabulary